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Targeted Therapy vs Immunotherapy: Comparing Clinical Trials in the UK

Understand the key differences between targeted therapy and immunotherapy clinical trials and research opportunities

Overview

Targeted Therapy

Drugs designed to target specific molecular features of cancer (EGFR inhibitors, BRAF inhibitors, PARP inhibitors). Requires biomarker testing for eligibility.

UK Trials Recruiting: ~150+ recruiting

Immunotherapy

Stimulates the patient's own immune system to attack cancer. Checkpoint inhibitors are the most common class. Biomarker testing (PD-L1, TMB) helps predict response.

UK Trials Recruiting: ~200+ recruiting

Key Differences for Trial Seekers

Targeted therapies require specific mutations. Immunotherapy depends on the tumour's immune environment. Both are precision medicine but work through different mechanisms.

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Data sourced from ClinicalTrials.gov. Trial counts are approximate and updated regularly.

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