UK clinical trials - updated daily from ClinicalTrials.gov
Find clinical trials for type 1 diabetes in the United Kingdom. Explore treatment pathways including artificial pancreas, islet cell transplantation, and immunotherapy.
Type 1 diabetes affects ~400,000 people in the UK. It is an autoimmune condition where the immune system destroys insulin-producing beta cells in the pancreas. Unlike type 2 diabetes, it is not related to lifestyle or weight. It can develop at any age but is most commonly diagnosed in childhood or young adulthood. Everyone with T1D requires lifelong insulin therapy.
Insulin delivery has advanced from multiple daily injections to insulin pumps and now hybrid closed-loop systems (artificial pancreas). The NHS is rolling out closed-loop technology nationally. Continuous glucose monitoring (CGM) like Dexcom and Libre is now standard NHS care. Islet cell transplantation is available for severe hypoglycaemia unawareness through specialised centres.
Exciting developments in T1D research include: immunotherapy to preserve beta cell function at diagnosis (teplizumab, approved in the US), stem cell-derived islet transplantation (Vertex VX-880 showing remarkable results), advanced closed-loop systems, smart insulin (glucose-responsive), and encapsulation technologies to protect transplanted cells without immunosuppression.
The UK is a world leader in T1D research through JDRF-funded programmes and NHS trial networks. Active areas: immunotherapy for newly diagnosed T1D, stem cell therapies, next-generation closed-loop systems, prevention trials for at-risk relatives, and complication prevention. Many trials are available through NHS diabetes centres and specialist hospitals.
Free AI-powered matching - no signup required
Search type 1 diabetes Trials →