🇬🇧United Kingdom clinical trials — updated daily from ClinicalTrials.gov + ISRCTN
TrialConnect
Help & Support

Frequently Asked Questions

81+ answers about finding UK clinical trials, eligibility, matching, paid studies, privacy, and safety. Can't find what you need? Get in touch.

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About TrialConnect

What is TrialConnect?

TrialConnect is a free website that helps you search UK clinical trials and see which ones might be relevant to your condition. We list trials from public registries and use a matching tool to help you understand your options — you then contact the trial team directly to find out more.

Is TrialConnect free to use?

Yes. TrialConnect is always free for patients — there are no paywalls, subscriptions, or hidden fees. We're funded by research sponsors, not by charging patients.

Who runs TrialConnect?

TrialConnect is run by TA Clinical Solutions Limited, a company registered in England (company number 17135935), registered office 17 Central Avenue, Herne Bay, Kent, CT6 8RX.

Is TrialConnect part of the NHS?

No. TrialConnect is an independent platform and is not affiliated with the NHS or NIHR. Many of the trials listed do take place at NHS hospitals, but TrialConnect itself is a separate, private company.

Where does TrialConnect get its trial data from?

Trial listings come from public registries, mainly ClinicalTrials.gov, the ISRCTN registry, and the NIHR portfolio. This data is publicly available, and we cannot guarantee it is always fully accurate or up to date — always check details with the trial team.

How many trials does TrialConnect cover?

We track thousands of UK clinical trials across many conditions, updated regularly from the registries above. Coverage varies by condition — some have many active trials, others have few or none at any given time.

Does TrialConnect only cover the UK?

TrialConnect's main focus is UK clinical trials. We're exploring other regions separately, but the matching tool and trial listings on this site are built around the UK trial landscape.

How does TrialConnect make money if it's free for patients?

Our revenue comes from research sponsors and organisations who value reaching pre-qualified, consented patients — not from charging patients. Sponsor funding does not affect which trials you're matched to or how they're ranked.

Using TrialConnect & Finding Trials

Do I need to create an account to search for trials?

No. You can pick your condition and see matches straight away without creating an account. An account is only needed if you want to save trials or manage alerts from a dashboard.

How do I search for a clinical trial?

Use the search or matching tool to choose your condition, then browse trials by location, phase, or keyword. You can also browse the full list of conditions and click through to see UK trials for each one.

What is the AI matching tool and how do I use it?

Our matching tool asks a short set of targeted questions about your condition, biomarkers, and treatment history, then scores currently recruiting UK trials against your answers. You don't need to sign up, and you can skip any question you're unsure about.

How is my match score calculated?

Each recruiting UK trial is scored against your answers across several factors — age, condition, biomarkers, prior treatments, and location. Open a trial's page and look for "Why am I matched?" to see the full breakdown. Your final eligibility is always confirmed by the trial team, not by TrialConnect.

Why does my match score start low and change as I answer questions?

At the start we know very little about your situation, so scores stay modest. As you answer more questions, the tool becomes more confident and the trials that fit you best move higher up the list.

Can I save trials to look at later?

Yes — if you create a free account you can save trials to your dashboard and come back to them later.

Can I sign up for alerts about new trials?

Yes. You can sign up for email alerts for a specific condition, and we'll let you know when a new matching trial opens for recruitment. Sign-up uses double opt-in, so you'll need to confirm your email before alerts start.

Eligibility & Matching

What does "eligibility criteria" mean?

Eligibility criteria are the rules a trial sets for who can take part — for example, age range, diagnosis, biomarkers, prior treatments, or general health. Every trial has its own criteria.

Does TrialConnect decide whether I'm eligible for a trial?

No. TrialConnect does not confirm eligibility, make clinical decisions, or provide medical advice. Our tool gives you an indication of fit; formal eligibility is always confirmed by the trial's own research team.

Why might I be excluded from a trial I'm interested in?

Trials exclude people for many reasons — for example current medications, other health conditions, previous treatments, or specific test results. This protects participant safety and keeps the trial's results reliable, and it isn't a judgement on you personally.

What if I'm not sure how to answer an eligibility question?

You can skip any question you're unsure about. The matching tool is designed to work with partial information — your score will simply reflect that some details are still unknown.

Can I still contact a trial team if I'm unsure whether I qualify?

Yes. If a trial looks relevant, it's worth contacting the research team directly — they can talk through your situation in detail, which the matching tool cannot do.

What are inclusion and exclusion criteria?

Inclusion criteria are the requirements you must meet to join a trial (for example, a specific diagnosis or age range). Exclusion criteria are conditions that would rule you out (for example, another illness or medication that could interfere with the study).

Do biomarkers or genetic test results affect my matches?

Yes, for many conditions — particularly cancers — biomarker or genetic results (such as specific mutations) can significantly change which trials are relevant. If you know your results, entering them can improve the accuracy of your matches.

Can healthy volunteers use TrialConnect?

Some trials, particularly early-phase (Phase 1) studies, recruit healthy volunteers rather than patients. You can search for these directly; our condition-based matching tool is mainly built around patients with a specific diagnosis.

What happens after I'm matched with a trial?

You'll see the trial's details, recruiting sites, and contact information. From there, you contact the trial team yourself — TrialConnect doesn't submit an application on your behalf or manage enrolment.

Understanding Clinical Trials

What is a clinical trial?

A clinical trial is a research study involving people that tests whether a new treatment, device, or approach is safe and effective. Trials are one of the main ways new medicines and treatments are developed and approved.

What are the phases of a clinical trial (Phase 1, 2, 3, 4)?

Phase 1 trials mainly test safety in a small group, often healthy volunteers. Phase 2 tests effectiveness and side effects in a larger group of patients. Phase 3 compares the new treatment with standard care in a large group, often across multiple hospitals. Phase 4 studies happen after a treatment is approved, to monitor long-term safety and effects.

What is a control group or placebo?

A control group receives either the standard existing treatment or, in some trials, a placebo (an inactive substance), so researchers can compare results against the new treatment. Not every trial uses a placebo — this varies by study, and trial information will state clearly whether one is used.

What does "randomised" mean in a clinical trial?

In a randomised trial, participants are assigned by chance to different treatment groups, rather than the researchers or participants choosing. This helps make sure the groups are as similar as possible, so the results are fair and reliable.

What is informed consent?

Informed consent means the research team explains the trial — what's involved, the possible benefits and risks — before you decide whether to take part. You sign (or, for digital trials, electronically confirm) a consent form, and you can ask questions at any point before agreeing.

Can I leave a trial after I've joined?

Yes. You can withdraw from a clinical trial at any time, for any reason, without it affecting your normal NHS care.

Where can I learn more about how clinical trials work?

Our Learn hub has plain-English guides covering what a clinical trial is, the four phases, your rights as a participant, what happens when you enrol, common myths, and questions to ask your doctor.

Safety, Regulation & Your Rights

Are clinical trials in the UK safe?

UK clinical trials must follow strict standards set by the MHRA and be approved by an independent research ethics committee before they can start. Risks are assessed in advance, and participants are monitored throughout — but as with any medical research, no trial can be guaranteed completely risk-free.

Who regulates clinical trials in the UK?

The Medicines and Healthcare products Regulatory Agency (MHRA) regulates clinical trials in the UK, alongside independent research ethics committees and NHS governance frameworks.

What are my rights as a trial participant?

You have the right to receive clear information before agreeing to take part, to ask questions, to withdraw at any time without giving a reason, and to have your normal NHS care continue unaffected. Our Learn hub has a full guide to your rights as a participant.

Can I withdraw from a trial at any time?

Yes, you can withdraw at any point, for any reason, and this will not affect your standard NHS care or treatment.

Will taking part in a trial affect my normal NHS care?

No — taking part in a clinical trial, or withdrawing from one, should not affect your right to normal NHS care. If you're ever unsure, this is a good question to raise directly with the trial team or your usual clinician.

Do I need to tell my GP or specialist if I join a trial?

It's good practice to keep your GP or specialist informed, since they manage your overall care and may need to know about any trial medication or procedures. Many trials will ask for your consent to inform your GP as part of the process.

What questions should I ask before joining a trial?

Useful questions include: what does taking part involve day-to-day, what are the possible risks and benefits, can I withdraw at any time, will it affect my current treatment, and who do I contact with concerns? Our Learn hub has a printable checklist of questions to ask.

What happens if something goes wrong during a trial?

Every UK trial has a process for reporting side effects or problems, and the research team must monitor participant safety throughout. If you have concerns during a trial, contact the research team directly using the details on your trial's information.

Privacy & Your Data

What personal data does TrialConnect collect?

We collect your email and name if you contact us, your health condition and matching questionnaire answers when you use the matching tool, and, where you consent, analytics about how you use the site. We do not collect NHS medical records, NHS numbers, or dates of birth.

Does TrialConnect store my health information?

Matching questionnaire answers are used to calculate your results and are not stored on our servers once your matching request is complete. If you save trials or sign up for alerts, that information is kept only for that purpose.

Does TrialConnect sell my data?

No. We do not sell identifiable patient data, and we will never sell your personal data.

Is TrialConnect GDPR compliant?

Yes. We process personal data under UK GDPR, relying on your explicit consent — including separate explicit consent for special category health data. We're registered with the Information Commissioner's Office (ICO), registration number ZC155240.

Who is TrialConnect's data protection contact?

You can reach us about privacy or data protection questions at admin@trialconnect.co.uk. Full details are in our Privacy Policy.

What cookies does TrialConnect use?

We use a small number of essential and analytics cookies, including a one-year session cookie. We don't use advertising cookies. You can review and change your cookie preferences from the link in the site footer.

Can I ask TrialConnect to delete my data?

Yes. You can ask us to access, correct, or delete your personal data at any time by emailing admin@trialconnect.co.uk. We aim to respond to data requests within 30 days.

Does an algorithm make decisions about me?

Our matching tool scores trials against your answers, but it does not make any decision about your care or eligibility — that's always confirmed by the trial team. You also have the right to request human review of any algorithmic matching decision.

How do I make a complaint about how my data is handled?

You can contact us directly at admin@trialconnect.co.uk. If you're not satisfied with our response, you have the right to complain to the Information Commissioner's Office (ico.org.uk).

Digital & Remote Trials

What is a digital or decentralised clinical trial?

A digital (or decentralised) clinical trial uses technology — apps, wearable sensors, and video consultations — so you can take part from home or your local area, with fewer hospital visits than a traditional trial.

How do remote clinical trials work?

Typically you complete consent and initial screening online, receive any study materials or devices by post, then join virtual check-ins and report symptoms through an app. Some digital trials still require one or two in-person visits.

What technology do I need for a digital trial?

Most digital trials need a smartphone and internet access. Some provide a wearable device, such as a smartwatch or sensor, as part of the study.

Are digital trials available through the NHS?

Yes, a growing number of NHS-supported studies now include digital or remote components, and this approach is actively encouraged as part of making research more widely accessible.

Who is a digital trial suitable for?

Digital trials can particularly suit people who live far from a research hospital, have mobility difficulties, or have busy schedules — though suitability always depends on the individual trial's own criteria.

Can I filter for telemedicine-friendly trials on TrialConnect?

Yes — you can filter trial search results for telemedicine-friendly or digital trial options, or visit our dedicated Digital Clinical Trials page.

For Clinicians & Referrers

Does TrialConnect have a tool for clinicians?

A dedicated clinician portal is in development and not yet live. In the meantime, clinicians can browse trial listings on the main site in the same way as patients.

What will the clinician portal offer when it launches?

Planned features include biomarker-based filtering, trial design filters, patient pipeline management, NHS site matching, and FHIR-ready data integration.

Can I refer a patient to a trial through TrialConnect?

There isn't yet a formal referral workflow. For now, clinicians and patients can use the site to identify potentially relevant trials, then contact the trial team directly.

Is the clinician portal NHS-integrated?

NHS integration — including NHS Care Identity (CIS2) authentication and NHS Digital endpoints — is part of the roadmap for the clinician portal, alongside a DTAC assessment and a DCB 0129/0160 clinical safety case. None of this is live yet.

How can a clinician get early access to the clinician portal?

You can join the waitlist from the clinician page, or email admin@trialconnect.co.uk to register interest in early access.

For Sponsors & Researchers

What does TrialConnect offer trial sponsors and CROs?

We offer sponsors and CROs pre-qualified, consented patient matches, plus a sponsor dashboard for managing recruitment. Visit our For Sponsors page for details.

Where does TrialConnect source its trial data from for sponsors?

Trial listings are sourced from ClinicalTrials.gov, the ISRCTN registry, and the NIHR portfolio. Patient matching data comes only from patients who have used TrialConnect's own matching tool and opted in.

Do sponsors see patients who haven't opted in?

No. Sponsors never see patients who have not explicitly opted in to being contacted about a specific trial.

Does sponsor funding affect which trials I'm matched to?

No. Sponsor funding pays for the platform, but it does not influence your match score or where a trial appears in your results — no paid placement affects matching or ranking.

How quickly can a sponsor get set up on TrialConnect?

Typical onboarding — including custom matching criteria and a sponsor dashboard — takes around one to two weeks, though this can vary by trial complexity.

How can a sponsor get in touch?

Email admin@trialconnect.co.uk with "Sponsor Partnerships" in the subject line, or use the contact form and select the sponsor enquiry option.

Account, Technical & Support

Do I need to be a certain age to use TrialConnect?

Yes. You must be at least 18 years old to use the trial matching service. If you're looking for trials for a child, speak to their clinical care team or search ClinicalTrials.gov directly.

Is TrialConnect available outside the UK?

The core site is built around UK clinical trials. We're aware of interest in other regions and may expand there in future, but this isn't the current focus.

How do I contact TrialConnect?

Email admin@trialconnect.co.uk, or use the contact form on our Contact page.

How quickly will I get a response?

We aim to respond within one to two business days. Urgent patient safety concerns are prioritised.

What if I can't find a trial for my condition?

Not every condition has an actively recruiting UK trial at any given time. You can sign up for email alerts so we notify you as soon as a relevant trial opens.

Can family members use TrialConnect on behalf of someone else?

Yes, a family member can search and use the matching tool on someone else's behalf. Keep in mind the person using the tool must still be 18 or older, and any decision to join a trial is ultimately made by the patient (or their legal representative).

Does TrialConnect work on mobile devices?

Yes, the site is designed to work on both desktop and mobile browsers.

What should I do if I find an error on the site?

Please let us know at admin@trialconnect.co.uk — we rely on public registry data, which can occasionally be outdated or incomplete, and we appreciate reports of anything that looks wrong.

This page is for general information only and is not medical advice. TrialConnect does not confirm eligibility, make clinical decisions, or guarantee trial outcomes or compensation — formal eligibility and participation are always confirmed by the relevant trial team. Trials in the UK are regulated by the MHRA and conducted under NHS governance. Always discuss with your doctor before making any decisions.

Still have questions?

Our free AI matching tool can show you relevant UK trials in a couple of minutes, or you can get in touch with our team directly.